Pirh2 Monoclonal Antibody, 100ul Pathway and Network Analysis RPL36 encodes a ribosomal protein

RPL36 encodes a ribosomal protein that is a component of the 60S subunit

Potent inhibitor of E2F-mediated trans-activation| associates preferentially with E2F5

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Alternate splicing generates multiple transcript variants encoding distinct isoforms

This gene encodes a highly conserved| putative transmembrane protein

Pirh2 Monoclonal Antibody, 100ul Pathway and Network Analysis RPL36 encodes a ribosomal proteinThe protein encoded by this gene has ubiquitin ligase activity. It mediates E3 dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.