PARP8 Polyclonal Antibody, 20ul Gloves The encoded protein is also

The encoded protein is also a candidate tumor suppressor protein| and aberrant promoter methylation of this gene may play a role in cervical cancer

The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit

SH3BGR (SH3 Domain Binding Glutamate Rich Protein) is a Protein Coding gene

autosomal dominant or X-linked inheritance

Subfamily A contains 12 genes| subfamily B contains 7 genes and 2 pseudogenes| and the more distantly related subfamily C contains 3 genes

PARP8 Polyclonal Antibody, 20ul Gloves The encoded protein is alsoCatalytic activity: NAD(+) + (ADP D ribosyl)(n) acceptor = nicotinamide + (ADP D ribosyl)(n+1) acceptor.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence Contaminating sequence. Potential poly A sequence.,Contains 1 PARP catalytic domain.,