Phospho-B23 (T199) Polyclonal Antibody, 50ul Buffer Solutions Decreased transcriptional expression of this

Decreased transcriptional expression of this gene is associated with various tumors

Mutations in this gene cause complement component 5 deficiency

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The encoded protein may also play a role in synaptic maturation during cortical development

Phospho-B23 (T199) Polyclonal Antibody, 50ul Buffer Solutions Decreased transcriptional expression of thisNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.