SAMHD1 Polyclonal Antibody, 20ul Gloves Inhibits the DNA-binding activity of

Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA

The E74 like ETS transcription factor 1 is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes

These defects can result in a lifelong bleeding tendency

is thought to be inactive because it lacks several residues required for activity

May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain

SAMHD1 Polyclonal Antibody, 20ul Gloves Inhibits the DNA-binding activity ofSAMHD1 may play a role in regulation of the innate immune response. The SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi Goutieres syndrome.