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Human Mannosyl-oligosaccharide 1, MAN1A1 ELISA Kit, 96T Immunoassays The core clock genes: PER1/2/3

Human Mannosyl-oligosaccharide 1, MAN1A1 ELISA Kit, 96T Immunoassays The core clock genes: PER1/2/3

Name: Human Mannosyl-oligosaccharide 1, MAN1A1 ELISA Kit, 96T Immunoassays The core clock genes: PER1/2/3
Brand: cgm.lt
SKU: 75188347210
Price: 185.49 USD
Availability: InStock
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SKU: 75188347210

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Human Mannosyl-oligosaccharide 1, MAN1A1 ELISA Kit, 96T Immunoassays The core clock genes: PER1/2/3

Store: cgm.lt · Domain: cgm.lt

Description

The core clock genes: PER1/2/3 and CRY1/2 which are transcriptional repressors form the negative limb of the feedback loop and interact with the CLOCK|NPAS2-ARNTL/BMAL1|ARNTL2/BMAL2 heterodimer inhibiting its activity and thereby negatively regulating their own expression

automatic self-diagnostics

This gene is located in a cluster of related genes on chromosome 19 and there is a pseudogene for this gene on chromosome 3

The GoLoco 1 and/or GoLoco 3 domains exhibit GDI activity towards GDP-bound G(i) alpha protein

Phosphorylates ARNTL/BMAL1 at 'Ser-17' and 'Ser-21' and primes it for ubiquitination and proteasomal degradation (PubMed: 28903391)

Human Mannosyl-oligosaccharide 1, MAN1A1 ELISA Kit, 96T Immunoassays The core clock genes: PER1/2/3

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