Rabbit Cyclooxygenase-2, COX-2 ELISA Kit, 96T PCR Series including 15-oxo-PGE1

including 15-oxo-PGE1

This protein may be the target of oncogenic mutations in breast or ovarian cancer

GNPAT (glyceronephosphate O-acyltransferase) encodes an enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids

The encoded protein is activated by oxidative stress and confers susceptibility to cell death

Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR)

Rabbit Cyclooxygenase-2, COX-2 ELISA Kit, 96T PCR Series including 15-oxo-PGE1Dual cyclooxygenase and peroxidase in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate, with a particular role in the inflammatory response. The cyclooxygenase activity oxygenates arachidonate (AA, C20: 4(n 6)) to the hydroperoxy endoperoxide prostaglandin G2 (PGG2), and the peroxidase activity reduces PGG2 to the hydroxy endoperoxide PGH2, the precursor of all 2 series prostaglandins and thromboxanes.