Angiomotin-L1 Polyclonal Antibody, 100ul Shaker&Mixing activation

activation

Members of the WIPI subfamily of WD40 repeat proteins| such as WIPI2| have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al

This gene encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family

Mutations in this gene have been linked to severe spermatogenic failure and infertility in males

this protein may act as a trigger for parturition

Angiomotin-L1 Polyclonal Antibody, 100ul Shaker&Mixing activationAngiomotin like protein 1 encoded by AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene.