XPA Polyclonal Antibody, 50ul Organelle Studies This protein induces apoptosis in

This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway

Studies in both human and mice suggest that PP1 is an important regulator of cardiac function

which is considered crucial to nuclear body interactions

mediate apoptosis

An additional variant encoding a different isoform has also been found for this gene

XPA Polyclonal Antibody, 50ul Organelle Studies This protein induces apoptosis inXPA encodes a zinc finger protein involved in DNA excision repair. The DNA repair protein complementing XP A cells is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.