PHLD Polyclonal Antibody, 20ul Nucleic Acid Amplification Defects in TMEM237 are a

Defects in TMEM237 are a cause of Joubert syndrome-14

Ran-dependent mechanism

Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome

HOXB9 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain

Yeast Mob1 binds Mps1p

PHLD Polyclonal Antibody, 20ul Nucleic Acid Amplification Defects in TMEM237 are aMany proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma