GATA-1 Polyclonal Antibody, 100ul[BT-AP03480] Pasteur Pipets Since the sim gene plays

Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis|it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics)| abnormalities of brain development| and/or mental retardation of Down syndrome

The protein belongs to the S3AE family of ribosomal proteins

RPS8 encodes a ribosomal protein that is a component of the 40S subunit

An important paralog of this gene is TLDC2

This locus encodes the transforming growth factor (TGF)-beta type III receptor

GATA-1 Polyclonal Antibody, 100ul[BT-AP03480] Pasteur Pipets Since the sim gene playsGATA1 encodes Erythroid transcription factor which belongs to the GATA family of transcription factors. Erythroid transcription factor plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in GATA1 have been associated with X linked dyserythropoietic anemia and thrombocytopenia.