Gab 2 Polyclonal Antibody, 50ul[BT-AP03410] Serological Pipets This gene functions as a

This gene functions as a tumor suppressor gene

Mutations in this gene are associated with congenital stationary night blindness type 1E

This gene encodes a protein similar to guanosine nucleotide exchange factors for Rho GTPases

Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females

Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6)

Gab 2 Polyclonal Antibody, 50ul[BT-AP03410] Serological Pipets This gene functions as aGAB2 (GRB2 associated binding protein 2) is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. The protein encoded by GAB2 is the principal activator of