Nephrocystin-5 Polyclonal Antibody, 50ul PCR Series At least three alternatively spliced

At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene

Mutations in this gene cause cerebellar ataxia in humans

Mutations in PEX2 result in one form of Zellweger syndrome and infantile Refsum disease

This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB

It also plays an important role in trafficking of T cells in thymus

Nephrocystin-5 Polyclonal Antibody, 50ul PCR Series At least three alternatively splicedIQCB1 encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. IQ calmodulin binding motif containing protein 1 has a central coiled coil region and two calmodulin binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. IQ calmodulin binding motif containing protein 1 is thought to play a role in ciliary function. Defects