DHX58 Polyclonal Antibody, 20ul Centrifugal Filter Mutations in PEX10 result in

Mutations in PEX10 result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders

This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine

Protein transport

Mutations in this gene are associated with Cenani-Lenz syndrome

May play a role in the defense system against microorganisms

DHX58 Polyclonal Antibody, 20ul Centrifugal Filter Mutations in PEX10 result inNegative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58 mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA.,Belongs to the helicase family.,Contains 1 helicase ATP binding domain.,Contains 1 helicase C terminal domain.,subunit: Interacts with DDX58 and probably blocks its homomultimerization.,