PAPP1 Polyclonal Antibody, 100ul Glassware Sets Mutations in this gene

Mutations in this gene

The protein encoded by this gene is a Rab-GTPase-activating protein| and contains two phopshotyrosine-binding domains (PTB1 and PTB2)| a calmodulin-binding domain (CBD)| a Rab-GTPase domain| and multiple AKT phosphomotifs

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This makes them ideal for expressing large DNA segments

modifier of

PAPP1 Polyclonal Antibody, 100ul Glassware Sets Mutations in this geneThis gene encodes a secreted metalloproteinase which cleaves insulin like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.