MKP-1 Polyclonal Antibody, 50ul Cell fragmentation and collection PubMed: 18305108)

PubMed: 18305108)

In humans deficiency of this protein is associated with increased risk of meningococcal infections

The encoded type 2 transmembrane protein may play a role in inflammatory and immune response

The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle

acting downstream of MAP3K7/TAK1 to phosphorylate STAT3

MKP-1 Polyclonal Antibody, 50ul Cell fragmentation and collection PubMed: 18305108)The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative heat stress and growth factors. It specifies a protein with structural features similar to members of the non receptor type protein tyrosine phosphatase family, and which has significant amino acid sequence similarity to a Tyr Ser protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase