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p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11731] Monoclonal Antibody Preparation ZMIZ2 and ZMIZ1 (MIM 607159)

SKU: 83306305689

4.3
PLN97.20 PLN137.20

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p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11731] Monoclonal Antibody Preparation ZMIZ2 and ZMIZ1 (MIM 607159)This gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

Store: cgm.lt · Domain: cgm.lt

Description

ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors

Matrix metalloproteinase-16 activates MMP2 by cleavage

They also suppress a number of genes including MCAM/MUC18

and has glycosaminoglycan attachment sites in the acidic C-terminal region

The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide

p53 Rabbit Polyclonal Antibody, 20ul[BT-AP11731] Monoclonal Antibody Preparation ZMIZ2 and ZMIZ1 (MIM 607159)This gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative

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