NFKappaB-p105 Polyclonal Antibody, 50ul[BT-AP05980] Thermal Control Certain mutations in this gene

Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia

hypertrophic DCM

It has been suggested to be involved in several basic biological events such as cell death

serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al

like other members of the family

NFKappaB-p105 Polyclonal Antibody, 50ul[BT-AP05980] Thermal Control Certain mutations in this geneNFKB1 encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF kappa B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra and extra cellular stimuli such as cytokines, oxidant free radicals, ultraviolet irradiation, and