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Rb(Phospho Ser612) Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) including interferon beta chain genes

SKU: 8403127047

4.6
USD123.75 USD169.75

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Rb(Phospho Ser612) Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) including interferon beta chain genesThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

including interferon beta chain genes

where it is transcriptionally regulated by AP-2epsilon and Ets-1

and to a lesser extent

Dual specificity mitogen-activated protein kinase kinase 6 phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress

defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease

Rb(Phospho Ser612) Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) including interferon beta chain genesThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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