Gab 1(Phospho Tyr659) Polyclonal Antibody, 100ul Digital Burette Defects in this gene are

Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2)

Highly expressed in testis

The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24

which binds to the core promoter to position the polymerase properly

Isoform 3 is catalytically inactive

Gab 1(Phospho Tyr659) Polyclonal Antibody, 100ul Digital Burette Defects in this gene areThe protein encoded by this gene is a member of the IRS1 like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.