MAGA3 Polyclonal Antibody, 50ul Gene Synthesis Might function by either activating

Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival

It plays a negative regulatory role in the Ras-Raf1-MAPK pathway| and knockout mice have been shown to develop spontaneous tumors| suggesting a role as a tumor suppressor gene

subunit:Interacts with SLIT2 and ENAH

function:Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF

Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias

MAGA3 Polyclonal Antibody, 50ul Gene Synthesis Might function by either activatingThis gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some