FKB1A Polyclonal Antibody, 100ul Immunology This gene encodes a member

This gene encodes a member of the tyrosine kinase and| more specifically| the Janus kinases (JAKs) protein families

The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth| development and metastasis

subcellular location:Distributed throughout the cytoplasm and also localizes to the perinuclear region of both human erythroleukemia (HEL) cells and Jurkat cells

Huntington's disease and temporal lobe epilepsy

A mutation in this gene was found in a family with Stickler syndrome

FKB1A Polyclonal Antibody, 100ul Immunology This gene encodes a memberThe protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF beta receptor. It also interacts with multiple intracellular calcium