Ksr-1(Phospho Ser392) Polyclonal Antibody, 50ul Proteases It is ubiquitously expressed in

It is ubiquitously expressed in normal tissues and in tumor cells

This isozyme is secreted

which has sequence-specific distal enhancer binding RNA polymerase II transcription-factor activity

The PHOX domain is a phosphoinositide binding domain| and the SNX family members are involved in intracellular trafficking

Also binds iron-free LCN2 (apo-24p3)

Ksr-1(Phospho Ser392) Polyclonal Antibody, 50ul Proteases It is ubiquitously expressed inThe sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,Location regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.,PTM: Phosphorylated on Ser 309 and, to a higher extent, on Ser 404 by MARK3. Dephosphorylated on Ser 404 by PPP2CA.