SETBP Rabbit Polyclonal Antibody, 20ul Immunology It has been shown to

It has been shown to play a central role in the physiological regulation of programmed cell death

preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres

Pseudogenes are present on chromosomes 5 and 22

alternative products:At least 4 isoforms| Alpha (shown here)| Alpha-B| Beta and Beta-B| are produced by alternative initiation at Met-1 and Met-27

This protein participates in the signal transduction of CD40

SETBP Rabbit Polyclonal Antibody, 20ul Immunology It has been shown toThis gene encodes a protein which contains a several motifs including a ski homology region and a SET binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.