Insulin R Polyclonal Antibody, 20ul[BT-AP04563] Monoclonal Antibody Preparation of a signal peptide

of a signal peptide

Mutations in NR3C are associated with generalized glucocorticoid resistance

GO annotations related to this gene include G-protein coupled receptor activity and neuropeptide binding

Low affinity immunoglobulin gamma Fc region receptor II-a encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils

Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking

Insulin R Polyclonal Antibody, 20ul[BT-AP04563] Monoclonal Antibody Preparation of a signal peptideINSR encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the