ALK Polyclonal Antibody, 50ul[BT-AP00371] Culture Plate Inserts The C-terminal fragment localizes to

The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus

Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2

The RoSSA particle localizes to both the cytoplasm and the nucleus

The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B

studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras

ALK Polyclonal Antibody, 50ul[BT-AP00371] Culture Plate Inserts The C-terminal fragment localizes toALK encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. ALK tyrosine kinase receptor comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or