PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling The protein (ataxin 2) encoded

The protein (ataxin 2) encoded by ATXN2 has two globular domains near the N-terminus

suggesting that it may also play an important role in cells undergoing rapid cell division

It seems to interact in a multiprotein complex with RbAp48 and HDAC3

100% integrity test Sterilized and non-sterilized available

Several transcript variants encoding different isoforms have been found for PPP1R12A

PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling The protein (ataxin 2) encodeddisease: Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM: Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM: