Beta-Catenin Polyclonal Antibody, 50ul Organelle Studies This gene is located in

This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis

This protein may be the target of oncogenic mutations in breast or ovarian cancer

Highly expressed in a number of intrahepatic cholangiocarcinoma tissue biopsies

Combined with high-throughput sequencing technology

USP45 (Ubiquitin carboxyl-terminal hydrolase 45)

Beta-Catenin Polyclonal Antibody, 50ul Organelle Studies This gene is located inThe protein encoded by CTNNB1 (catenin beta 1) is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.