CHD8 Polyclonal Antibody, 50ul Human Genome Knockout Libraries and three alternative downstream AUG

and three alternative downstream AUG initiation codons

It is also found to be expressed in lipogenic breast cancers| which suggests a role in controlling tumor lipid metabolism

EPHB6 encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins

and pluripotency

HMGB1 encodes a protein that belongs to the High Mobility Group-box superfamily

CHD8 Polyclonal Antibody, 50ul Human Genome Knockout Libraries and three alternative downstream AUGThis gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.