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The encoded protein is involved in natural killer cell development and function

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which is required for production of the sex hormones

Grap Polyclonal Antibody, 20ul Modification Enzymes No more settling for averageGRAP encodes a member of the GRB2 Sem5 Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through