TIG1 Polyclonal Antibody, 100ul Immunoassays Mutations in ACVR1B are associated

Mutations in ACVR1B are associated with pituitary tumors

It is activated by a range of compounds that induce CYP3A4

but mutations in this gene have not been associated with the disease

This gene exhibits tissue-specific imprinting

The protein plays a role in pre-mRNA processing

TIG1 Polyclonal Antibody, 100ul Immunoassays Mutations in ACVR1B are associatedThis gene was identified as a retinoid acid (RA) receptor responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.