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PBF Polyclonal Antibody, 50ul Drug Development and Evaluation The epitopes that elicit these

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PBF Polyclonal Antibody, 50ul Drug Development and Evaluation The epitopes that elicit thesePTTG1IP (pituitary tumor transforming 1 interacting protein) encodes a single pass type I integral membrane protein, which binds to pituitary tumor transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for PTTG1IP.

Store: cgm.lt · Domain: cgm.lt

Description

The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein

and polymorphisms that alter expression of ERCC1 may play a role in carcinogenesis

This gene encodes a member of the SH2B adaptor family of proteins

Additional variants have been observed| but their full-length natures have not been determined

which are involved in a range of signaling activities by growth factor and cytokine receptors

PBF Polyclonal Antibody, 50ul Drug Development and Evaluation The epitopes that elicit thesePTTG1IP (pituitary tumor transforming 1 interacting protein) encodes a single pass type I integral membrane protein, which binds to pituitary tumor transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for PTTG1IP.

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