IL-4R Alpha Polyclonal Antibody, 50ul[BT-AP04505] Erlenmeyer Flasks SIAH1 encodes E3 ubiquitin-protein ligase

SIAH1 encodes E3 ubiquitin-protein ligase SIAH1 that is a member of the seven in absentia homolog (SIAH) family

The gene product interacts specifically with the ligand binding domain

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and 5-hydroxy-6E

HNRNPLL is a master regulator of activation-induced alternative splicing in T cells

and is required for transcriptional activation by a variety of transcription factors

IL-4R Alpha Polyclonal Antibody, 50ul[BT-AP04505] Erlenmeyer Flasks SIAH1 encodes E3 ubiquitin-protein ligaseIL4R encodes the alpha chain of the interleukin 4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. Interleukin 4 receptor subunit alpha also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane bound protein, and this soluble form can inhibit IL4 mediated cell proliferation and IL5