Human Sterol Regulatory Element-binding Protein 1, SREBF1 ELISA Kit , 96T Gloves it can function as a

it can function as a co-repressor of androgen-responsive gene expression

Alternate splicing of this gene results in three transcript variants encoding different isoforms

cell motility and morphogenesis in numerous cell and tissue types

Mutations of ankyrin genes lead to severe genetic diseases

It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin

Human Sterol Regulatory Element-binding Protein 1, SREBF1 ELISA Kit , 96T Gloves it can function as a[Sterol regulatory element binding protein 1]: Precursor of the transcription factor form (Processed sterol regulatory element binding protein 1), which is embedded in the endoplasmic reticulum membrane (PubMed: 32322062). Low sterol concentrations promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes involved in cholesterol biosynthesis and lipid homeostasis