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ASPM Polyclonal Antibody, 50ul Site-directed Mutagenesis HEY2 encodes a member of

SKU: 95051887523

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ASPM Polyclonal Antibody, 50ul Site-directed Mutagenesis HEY2 encodes a member ofThis gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found

Store: cgm.lt · Domain: cgm.lt

Description

HEY2 encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors

subcellular location:Seems to be excluded from nucleoli

a system implicated in the pathogeny of such psychiatric diseases as depression

It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription

Two transcript variants encoding different isoforms have been found for SLIT3

ASPM Polyclonal Antibody, 50ul Site-directed Mutagenesis HEY2 encodes a member ofThis gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found

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