GPVI Polyclonal Antibody, 20ul Serological Pipets Mutation and knockout studies of

Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis

Interacts with H

The carcinoembryonic antigen related cell adhesion molecule 3 directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac

is thought to be inactive because it lacks several residues required for activity

A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis

GPVI Polyclonal Antibody, 20ul Serological Pipets Mutation and knockout studies ofThis gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet type bleeding disorder 11