IOD2 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) Trichodentoosseous syndrome (TDO)

Trichodentoosseous syndrome (TDO)

This gene is mutated in congenital disorder of glycosylation type Ik

This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels

This gene encodes a transmembrane protein that is necesssary for mechanotransduction in cochlear hair cells of the inner ear

and RNA splicing

IOD2 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) Trichodentoosseous syndrome (TDO)The protein encoded by this gene belongs to the iodothyronine deiodinase family. It catalyzes the conversion of prohormone thyroxine (3,5,3',5' tetraiodothyronine, T4) to the bioactive thyroid hormone (3,5,3' triiodothyronine, T3) by outer ring 5' deiodination. This gene is widely expressed, including in thyroid, placenta, pituitary and brain. It is thought to be responsible for the 'local' production of T3, and thus important in influencing thyroid