CLC2D Polyclonal Antibody, 100ul Immunology disease:A chromosomal aberration involving FOXO3

disease:A chromosomal aberration involving FOXO3 is found in secondary acute leukemias

a tumor suppressor protein related to APC/beta-catenin signaling pathway

particularly on chromosomes Y and 15

Mutations in this gene are associated with metabolic syndrome

Required for efficient interaction with E1A

CLC2D Polyclonal Antibody, 100ul Immunology disease:A chromosomal aberration involving FOXO3This gene encodes a member of the natural killer cell receptor C type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N terminus as well as the C type lectin like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene.