CREL1 Polyclonal Antibody, 100ul Nucleic Acid Amplification AKT1S1 is a proline-rich substrate

AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH| MIM 113508) when phosphorylated (Kovacina et al

preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres

and its activity is regulated by both phosphorylation and acetylation

Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits

HOXA6 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression

CREL1 Polyclonal Antibody, 100ul Nucleic Acid Amplification AKT1S1 is a proline-rich substrateThis gene encodes a member of a subfamily of epidermal growth factor related proteins. The encoded protein is characterized by a cysteine rich with epidermal growth factor like domain. This protein may function as a cell adhesion molecule. Mutations in this gene are the cause of atrioventricular septal defect. Alternate splicing results in multiple transcript variants.