UBP14 Polyclonal Antibody, 20ul Cell Culture Dishes The synaptotagmins are integral membrane

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis

PTM:Phosphorylation on Thr-203 by PKA destabilizes the heterotrimer of alpha

suggesting that these molecules may act in concert to regulate secretory processes in plasma cells

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Mutations in this gene are associated with spondylepiphyseal dysplasia and humerospinal dysostosis

UBP14 Polyclonal Antibody, 20ul Cell Culture Dishes The synaptotagmins are integral membraneThis gene encodes a member of the ubiquitin specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age