IL-1RI(Phospho Tyr496) Polyclonal Antibody, 20ul Vacuum Filter Non-receptor tyrosine-protein kinase TYK2 associates

Non-receptor tyrosine-protein kinase TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits

It prefers the substrate of lacto-N-neotetraose

MAX dimerization protein)belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors

and it also acts as a tumor suppressor

Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization| inositol triphosphate production and secretion of IL6 and CSF1

IL-1RI(Phospho Tyr496) Polyclonal Antibody, 20ul Vacuum Filter Non-receptor tyrosine-protein kinase TYK2 associatesThis gene encodes a cytokine receptor that belongs to the interleukin 1 receptor family. The encoded protein is a receptor for interleukin 1 alpha, interleukin 1 beta, and interleukin 1 receptor antagonist. It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12.