SAE1 Polyclonal Antibody, 50ul ADME involving ubiquitin conjugating enzymes and

involving ubiquitin conjugating enzymes and deubiquitinating enzymes

This protein inhibits the growth and spread of some types of breast cancer

Among its related pathways are Transport of glucose and other sugars

Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia

and more specifically

SAE1 Polyclonal Antibody, 50ul ADME involving ubiquitin conjugating enzymes andPosttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO activating enzyme for the sumoylation of proteins.