Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include death receptor binding

and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins

inducing leukocyte migration and activation

Mitotic and Regulation of PLK1 Activity at G2/M Transition

Intermediate filamentents

Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma Gene Ontology (GO) annotations relatedMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.