Epetraborole hydrochloride - CAS# 1234563-16-6 size:2mg solid 8E)-N-(4-hydroxyphenyl)-3

8E)-N-(4-hydroxyphenyl)-3

348(2):167-76

Smiles: OC(=O)C1=CC2=NC(NC3=CC(Cl)=CC=C3)=C3C=CN=CC3=C2C=C1

PubMed PMID: 24840224

The extent of retinal neovascularization in a mouse OIR model is reduced by approximately 60% after treatment with TBB (6 days at 60 mg/kg per day)

Epetraborole hydrochloride - CAS# 1234563-16-6 size:2mg solid 8E)-N-(4-hydroxyphenyl)-3Epetraborole hydrochloride, CAS No. 1234563 16 6, also known as GSK2251052 and AN3365, is a potent and selective leucyl tRNA synthetase inhibitor. Epetraborole was in development for the treatment of infections caused by multidrug resistant Gram negative pathogens. GSK2251052 is a novel boron containing antibiotic that inhibits bacterial leucyl tRNA synthetase. All Clostridium perfringens strains had GSK2251052 MICs of >32 g ml. Product information