Bisindolylmaleimide I (GF109203X) - CAS# 133052-90-1 size:2mg solid thereby inhibiting tumor cell migration

thereby inhibiting tumor cell migration

J Contemp Dent Pract

223645-67-8 (free base)

InChi: InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H

It is completely inactive against type II and type III PRMTs

Bisindolylmaleimide I (GF109203X) - CAS# 133052-90-1 size:2mg solid thereby inhibiting tumor cell migrationBisindolylmaleimide I (GF109203X), a potent and highly selective PCK inhibitor., CAS No. 133052 90 1, is a potent and highly selective PCK inhibitor. bisindolylmaleimide I(GF 109203X )inhibits PKC isozymes alpha, beta 1, beta 2, gamma, delta and epsilon in vitro . GF 109203X inhibited GSK 3 in vitro, when assayed either in cell lysates (IC(50) 360 nM or in GSK 3beta immunoprecipitates (IC(50) 170 nM derived from rat epididymal adipocytes. Pretreatment