BMX-IN-1 - CAS# 1431525-23-3 0268 2) with lower affinity

2) with lower affinity

3 nM in a radioactive enzyme assay and is over 100-fold selective for other histone methyltransferases/HMTs

Fmk is an irreversible ribosomal S6 kinase inhibitor 1/2 inhibitor

Chemical Name: tert-butyl 2-{4

Molecular Weight: 897

BMX-IN-1 - CAS# 1431525-23-3 0268 2) with lower affinityBMX IN 1 is a selective irreversible BMX inhibitor for prostate cancer. BMX IN 1 can covalently modifies Cys496. BMX IN 1 inhibits the proliferation of Tel BMX transformed Ba F3 cells at two digit nanomolar concentrations but requires single digit micromolar concentrations to inhibit the proliferation of prostate cancer cell lines. MK2206, is able to potentiate BMX inhibitor's antiproliferation efficacy against prostate cancer cells. Product