AMG-208 - CAS# 1002304-34-8 K-4827 Tosylate 11aS)-10-[4-(dimethylamino)phenyl]-1-hydroxy-11a-methyl-1-(prop-1-yn-1-yl)-1H

11aS)-10-[4-(dimethylamino)phenyl]-1-hydroxy-11a-methyl-1-(prop-1-yn-1-yl)-1H

InChi: InChI=1S/C13H26O4/c1-2-3-4-5-6-7-8-9-13(16)17-11-12(15)10-14/h12

Formula: C27H28N4O3S2

3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methylpyridin-3-yl)-[1

CAS Number: 131875-08-6

AMG-208 - CAS# 1002304-34-8 K-4827 Tosylate 11aS)-10-[4-(dimethylamino)phenyl]-1-hydroxy-11a-methyl-1-(prop-1-yn-1-yl)-1HAMG 208 is a selective small molecule inhibitor of the proto oncogene c Met with potential antineoplastic activity. c Met inhibitor AMG 208 inhibits the ligand dependent and ligand independent activation of c Met, inhibiting its tyrosine kinase activity, which may result in cell growth inhibition in tumors that overexpress c Met. C Met encodes the hepatocyte growth factor receptor tyrosine kinase, plays an important role in epithelial cell