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Adavivint - CAS# 1467093-03-3 Catalog No.:M6927-2 1007647-73-5

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Adavivint - CAS# 1467093-03-3 Catalog No.:M6927-2 1007647-73-5Adavivint, CAS No. 1467093 03 3, also known as SM04690, is a small molecule inhibitor of the Wnt pathway which is being investigated as a potential disease modifying agent for the treatment of osteoarthritis of the knee Product information CAS Number: 1467093 03 3 Molecular Weight: 505. 55 Formula: C29H24FN7O Synonym: SM 04690 Chemical Name: N (5 (3 (7 (3 Fluorophenyl) 3H imidazo(4,5 C)pyridin 2 yl) 1H indazol 5 yl) pyridin 3 yl) 3 methylbutanamide

Store: cgm.lt · Domain: cgm.lt

Description

1007647-73-5

is a Wnt/β-catenin inhibitor

The highest dose (100 and 300ng) BMP4 treatments generate a gene expression signature most similar to osteoblast expression

MS023 potently reduces cellular levels of H4R3me2a in MCF7 and HEK293 cells by inhibiting PRMT1/6 methyltransferase activity with IC50 of 9 nM and 56 nM

Zarybnicka L

Adavivint - CAS# 1467093-03-3 Catalog No.:M6927-2 1007647-73-5Adavivint, CAS No. 1467093 03 3, also known as SM04690, is a small molecule inhibitor of the Wnt pathway which is being investigated as a potential disease modifying agent for the treatment of osteoarthritis of the knee Product information CAS Number: 1467093 03 3 Molecular Weight: 505. 55 Formula: C29H24FN7O Synonym: SM 04690 Chemical Name: N (5 (3 (7 (3 Fluorophenyl) 3H imidazo(4,5 C)pyridin 2 yl) 1H indazol 5 yl) pyridin 3 yl) 3 methylbutanamide

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