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XAV939 - Wnt Antagonist. CAS# 284028-89-3 075 J Glaucoma

XAV939 - Wnt Antagonist. CAS# 284028-89-3 075 J Glaucoma

Name: XAV939 - Wnt Antagonist. CAS# 284028-89-3 075 J Glaucoma
Brand: cgm.lt
SKU: 54056021273
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SKU: 54056021273

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XAV939 - Wnt Antagonist. CAS# 284028-89-3 075 J GlaucomaXAV939, CAS No. 284028 89 3, is a potent and selective Wnt pathway antagonist. It functions to stabilize Axin by inhibiting the poly ADP ribosylating enzymes tankyrase 1 and tankyrase 2 with IC50 of 11 nM and 4 nM, respectively. It has been used to study Wnt dependent cancers. In addition, XAV939 was shown to stabilize Axin2 level in oligodendrocyte precursor cells in the spinal cord and accelerated their differentiation and myelination after hypoxic

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J Glaucoma

Jurkat cells)

Neurosci Res 86: 270-280

At 30-100 μM

20)11-5-10(6-12(7-11)17(21

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