TAK-733 Size:2mg solid 0b013e32835566c0

0b013e32835566c0

eCollection 2013

Divergent CFTR orthologs respond differently to the channel inhibitors CFTRinh-172

In an inflammation-induced anemia model in rats

a functional group that is subject to hydrolysis and/or other degradation mechanisms

TAK-733 Size:2mg solid 0b013e32835566c0TAK 733 is an orally bioavailable small molecule inhibitor of MEK1 and MEK2 (MEK1 2) with potential antineoplastic activity. MEK inhibitor TAK 733 selectively binds to and inhibits the activity of MEK1 2, preventing the activation of MEK1 2 dependent effector proteins and transcription factors, which may result in the inhibition of growth factor mediated cell signaling and tumor cell proliferation. MEK1 2 (MAP2K1 K2) are dual specificity threonine