Idasanutlin Size:10mg solid 1137868-52-0
SEK85.00
SEK131.00
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Idasanutlin Size:10mg solid 1137868-52-0Idasanutlin, also known as RG7388 and RO5503781, is a highly potent and selective MDM2 antagonist with potential anticancer activity. RG7388 binds to MDM2 blocking the interaction between the MDM2 protein and the transcriptional activation domain of the tumor suppressor protein p53. By preventing the MDM2 p53 interaction, p53 is not enzymatically degraded and the transcriptional activity of p53 is restored. This may lead to p53 mediated induction of
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